INTRAVENTRICULAR MET5-ENKEPHALIN CAUSES UNEXPECTED LOWERING OF PAIN THRESHOLD AND NARCOTIC WITHDRAWAL SIGNS IN RATS

被引：65
作者：
LEYBIN, L
PINSKY, C
LABELLA, FS
HAVLICEK, V
REZEK, M
机构：
[1] UNIV MANITOBA,FAC MED,DEPT PHARMACOL & THERAPEUTICS,WINNIPEG R3E OW3,MANITOBA,CANADA
[2] UNIV MANITOBA,FAC MED,DEPT PHYSIOL,WINNIPEG R3E OW3,MANITOBA,CANADA
来源：
NATURE | 1976年 / 264卷 / 5585期
关键词：
D O I：
10.1038/264458a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：458 / 459
页数：2
相关论文
共 25 条
[1]   ANALGESIA INDUCED INVIVO BY CENTRAL ADMINISTRATION OF ENKEPHALIN IN RAT [J].
BELLUZZI, JD ;
GRANT, N ;
GARSKY, V ;
SARANTAKIS, D ;
WISE, CD ;
STEIN, L .
NATURE, 1976, 260 (5552) :625-626
[2]   C FRAGMENT OF LIPOTROPIN HAS A HIGH AFFINITY FOR BRAIN OPIATE RECEPTORS [J].
BRADBURY, AF ;
SMYTH, DG ;
SNELL, CR ;
BIRDSALL, NJM ;
HULME, EC .
NATURE, 1976, 260 (5554) :793-795
[3]   TOLERANCE TO OPIOID NARCOTICS - TIME COURSE AND REVERSIBILITY OF PHYSICAL DEPENDENCE IN MICE [J].
CHENEY, DL ;
GOLDSTEIN, A .
NATURE, 1971, 232 (5311) :477-+
[4]  
CRAIG CR, 1968, J PHARMACOL EXP THER, V164, P371
[5]  
DEGROOT J, 1959, VERHANDELINGEN KONIK, V2, P3
[6]  
EIDELBERG E, 1974, ARCH INT PHARMACOD T, V211, P58
[7]  
FELDBERG W, IN PRESS
[8]  
GIGLIOTTI O, 1974, RODA ABSTR, P91
[9]  
GOLDSTEIN A, 1974, CAN FED BIOL SOC 17T
[10]  
GUILLEMIN R, 1976, CR ACAD SCI D NAT, V282, P783
123