ENANTIOSELECTIVITY AND REACTIVITY OF IMMOBILIZED LIPASE IN SUPERCRITICAL CARBON-DIOXIDE

被引：22

作者：

CERNIA, E ^{[1
]}

PALOCCI, C ^{[1
]}

GASPARRINI, F ^{[1
]}

MISITI, D ^{[1
]}

FAGNANO, N ^{[1
]}

机构：

[1] UNIV ROMA LA SAPIENZA,DIPARTIMENTO STUDI CHIM & TECNOL SOSTANZE BIOL ATT,I-00185 ROME,ITALY

来源：

JOURNAL OF MOLECULAR CATALYSIS | 1994年 / 89卷 / 1-2期

关键词：

CARBON DIOXIDE; ENZYMES; LIPASE; SUPERCRITICAL FLUIDS;

D O I：

10.1016/0304-5102(93)E0289-S

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Some results and some general observations on the reactivity of different substrates in lipase-catalyzed reactions in supercritical carbon dioxide are reported. Chiral 1-phenylethanol, 2-octanol, 6-methyl-5-hepten-2-ol and trans-3-penten-2-ol have been prepared in high enantiomeric excess (ee > 80%) by enantioselective acetylation of the corresponding racemic alcohols using immobilized crude lipase (Pseudomonas sp. from Amano) in supercritical carbon dioxide.

引用

页码：L11 / L18

页数：8

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[2]

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[3]

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[5]

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