ROLE OF RNA IN BACTERIOPHAGE-PHI-29 DNA PACKAGING

被引：16
|
作者：
ANDERSON, D [1 ]
BODLEY, JW [1 ]
机构：
[1] UNIV MINNESOTA,DEPT BIOCHEM,MINNEAPOLIS,MN 55455
来源：
JOURNAL OF STRUCTURAL BIOLOGY | 1990年 / 104卷 / 1-3期
关键词：
D O I：
10.1016/1047-8477(90)90059-L
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel bacteriophage φ29 RNA of 174 nucleotides is essential for the in vitro packaging of the DNA-terminal protein complex into proheads. The RNA, bound to the prohead portal vertex (connector), participates in assembly and function of the DNA translocating ATPase and in recognition of the DNA left-end during the course of the packaging reaction. The RNA is present in related phages and varies widely in primary sequence, but its secondary structure, as deduced by phylogenetic analysis, is both highly conserved and unique among small RNAs. © 1990.
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页码：70 / 74
页数：5
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