INCREASED BETA-CELL SECRETORY CAPACITY AS MECHANISM FOR ISLET ADAPTATION TO NICOTINIC-ACID INDUCED INSULIN RESISTANCE

被引：208
作者：
KAHN, SE
BEARD, JC
SCHWARTZ, MW
WARD, WK
DING, HL
BERGMAN, RN
TABORSKY, GJ
PORTE, D
机构：
[1] UNIV WASHINGTON,SCH MED,DEPT MED,SEATTLE,WA 98195
[2] UNIV SO CALIF,DEPT PHYSIOL & BIOPHYS,LOS ANGELES,CA 90089
来源：
DIABETES | 1989年 / 38卷 / 05期
关键词：
D O I：
10.2337/diabetes.38.5.562
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：562 / 568
页数：7
相关论文
共 52 条
[1]   EFFECT OF CORTICOSTERONE ON INSULIN AND GLUCAGON-SECRETION BY THE ISOLATED PERFUSED RAT PANCREAS [J].
BARSEGHIAN, G ;
LEVINE, R .
ENDOCRINOLOGY, 1980, 106 (02) :547-552
[2]   THE INSULIN SENSITIVITY INDEX IN NONDIABETIC MAN - CORRELATION BETWEEN CLAMP-DERIVED AND IVGTT-DERIVED VALUES [J].
BEARD, JC ;
BERGMAN, RN ;
WARD, WK ;
PORTE, D .
DIABETES, 1986, 35 (03) :362-369
[3]   DEXAMETHASONE-INDUCED INSULIN RESISTANCE ENHANCES B-CELL RESPONSIVENESS TO GLUCOSE LEVEL IN NORMAL MEN [J].
BEARD, JC ;
HALTER, JB ;
BEST, JD ;
PFEIFER, MA ;
PORTE, D .
AMERICAN JOURNAL OF PHYSIOLOGY, 1984, 247 (05) :E592-E596
[4]   RELATIONSHIP OF ISLET FUNCTION TO INSULIN ACTION IN HUMAN OBESITY [J].
BEARD, JC ;
WARD, WK ;
HALTER, JB ;
WALLUM, BJ ;
PORTE, D .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 65 (01) :59-64
[5]   QUANTITATIVE ESTIMATION OF INSULIN SENSITIVITY [J].
BERGMAN, RN ;
IDER, YZ ;
BOWDEN, CR ;
COBELLI, C .
AMERICAN JOURNAL OF PHYSIOLOGY, 1979, 236 (06) :E667-E677
[6]   EQUIVALENCE OF THE INSULIN SENSITIVITY INDEX IN MAN DERIVED BY THE MINIMAL MODEL METHOD AND THE EUGLYCEMIC GLUCOSE CLAMP [J].
BERGMAN, RN ;
PRAGER, R ;
VOLUND, A ;
OLEFSKY, JM .
JOURNAL OF CLINICAL INVESTIGATION, 1987, 79 (03) :790-800
[7]  
BERGMAN RN, 1986, METHODS DIABETES RES, V2, P15
[8]   POTENTIATION OF INSULIN RELEASE BY GLUCOSE IN MAN .3. NORMAL RECOGNITION OF GLUCOSE AS A POTENTIATOR IN SUBJECTS WITH LOW INSULIN-RESPONSE AND IN MILD DIABETES [J].
CERASI, E .
ACTA ENDOCRINOLOGICA, 1975, 79 (03) :511-534
[9]   PATHOGENESIS OF AGE-RELATED GLUCOSE-INTOLERANCE IN MAN - INSULIN RESISTANCE AND DECREASED BETA-CELL FUNCTION [J].
CHEN, M ;
BERGMAN, RN ;
PACINI, G ;
PORTE, D .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1985, 60 (01) :13-20
[10]   RESISTANCE TO INSULIN SUPPRESSION OF PLASMA-FREE FATTY-ACID CONCENTRATIONS AND INSULIN STIMULATION OF GLUCOSE-UPTAKE IN NONINSULIN-DEPENDENT DIABETES-MELLITUS [J].
CHEN, YDI ;
GOLAY, A ;
SWISLOCKI, ALM ;
REAVEN, GM .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 64 (01) :17-21
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