INHIBITION OF CYP1A, CYP2B, AND CYP3A ACTIVITIES BY 5HT3 ANTAGONISTS

被引：0

作者：

GAN, LS ^{[1
]}

BOEHLERT, C ^{[1
]}

THAKKER, D ^{[1
]}

SERABJITSINGH, C ^{[1
]}

机构：

[1] GLAXO RES INST,DEPT DRUG METAB,RES TRIANGLE PK,NC 27709

来源：

FASEB JOURNAL | 1994年 / 8卷 / 07期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：A1248 / A1248

页数：1

共 50 条

[21] Co-treatment with indole-3-carbinol and resveratrol modify porcine CYP1A and CYP3A activities and expression [J].

Zamaratskaia, Galia ;

Thogersen, Rebekka ;

Candek-Potokar, Marjeta ;

Rasmussen, Martin Kroyer .

XENOBIOTICA, 2018, 48 (03) :232-240

[22] Sex difference in induction of hepatic CYP2B and CYP3A subfamily enzymes by nicardipine and nifedipine in rats [J].

Konno, Y ;

Sekimoto, M ;

Nemoto, K ;

Degawa, M .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2004, 196 (01) :20-28

[23] Development of in vitro higher throughput CYP1A, CYP2B6 and CYP3A induction assays using probe cocktail approach [J].

Yu, Jingjing ;

Tang, Jun .

DRUG METABOLISM REVIEWS, 2009, 41 :87-87

[24] Effects of inhibitors of CYP1A and CYP2B on styrene metabolism in mouse liver and lung microsomes [J].

Carlson, GP ;

Hynes, DE ;

Mantick, NA .

TOXICOLOGY LETTERS, 1998, 98 (03) :131-137

[25] Humanized CYP3A Mice: (2) Functional Expression of Human CYP3A Isoforms in CYP3A-HAC Mice and Inhibition of CYP3A via Mechanism-Based Inactivation [J].

Watanabe, Mio ;

Aueviriyavit, Sasitorn ;

Kobayashi, Kaoru ;

Iuchi, Nahoko ;

Kazuki, Yasuhiro ;

Oshimura, Mitsuo ;

Chiba, Kan .

DRUG METABOLISM REVIEWS, 2010, 42 :30-31

[26] Effect of CYP3A5 genotype on the extent of CYP3A inhibition by verapamil. [J].

Wang, Y ;

Jin, Y ;

Hilligoss, JK ;

Ho, H ;

Hamman, MA ;

Hu, Z ;

Gorski, JC ;

Hall, SD .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 77 (02) :P3-P3

[27] Quantitative structure-activity relationship study of binding affinity of azole compounds with CYP2B and CYP3A [J].

Itokawa, Daisuke ;

Nishioka, Tomoki ;

Fukushima, Junji ;

Yasuda, Tomoyo ;

Yamauchi, Aiko ;

Chuman, Hiroshi .

QSAR & COMBINATORIAL SCIENCE, 2007, 26 (07) :828-836

[28] Dose response relationship for CYP1A and CYP3A in primary cultures of beagle dog hepatocytes [J].

Graham, RA ;

Czerwinski, M ;

Hamilton, G ;

Thompson, TN ;

Parkinson, A ;

LeCluyse, EL .

DRUG METABOLISM REVIEWS, 2003, 35 :124-124

[29] The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters [J].

Huan, JY ;

Miranda, CL ;

Buhler, DR ;

Cheeke, PR .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1998, 151 (02) :229-235

[30] Aldrin Epoxidation in Flathead Mullet (Mugil cephalus): Possible Involvement of CYP1A and CYP3A [J].

Bozcaarmutlu, Azra ;

Turna, Sema ;

Sapmaz, Canan ;

Arinc, Emel ;

Yenisoy-Karakas, Serpil .

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2014, 28 (06) :271-280

← 1 2 3 4 5 →