TERATOLOGIC ASSESSMENT OF MALEIC HYDRAZIDE AND DAMINOZIDE, AND FORMULATIONS OF ETHOXYQUIN, THIABENDAZOLE AND NALED IN RATS

被引：14

作者：

KHERA, KS

WHALEN, C

TRIVETT, G

ANGERS, G

机构：

[1] Bureau of Chemical Safety, New Research Centre, Tunney's Pasture, Ottawa

来源：

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES | 1979年 / 14卷 / 06期

关键词：

daminozide; embryotoxicity; ethoxyquin; maleic hydrazide; naled; Teratogenicity; thiabendazole;

D O I：

10.1080/03601237909372151

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Teratogenicity studies were conducted in rats treated orally from days 6–15 of gestation with single daily doses of 400–1600 mg/kg of maleic hydrazide, 300–1000 mg/kg daminozide, 125–500 mg/kg ethoxyquin or thiabendazole, or 25–100 mg/kg naled. Dams were killed on the 22nd day of gestation, and fetuses were evaluated by routine teratologic methods. No adverse effect was related to any treatment other than an increased incidence of anomalous fetuses at the highest dose (500 mg/kg) of thiabendazole. Copyright © 1979 by Marcel Dekker, Inc. All Rights Reserved.

引用

页码：563 / 577

页数：15

共 29 条

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