INDUCTION OF MICRONUCLEI IN GILL TISSUE OF MYTILUS-GALLOPROVINCIALIS EXPOSED TO POLLUTED MARINE WATERS

被引：76
作者：
SCARPATO, R
MIGLIORE, L
ALFINITOCOGNETTI, G
BARALE, R
机构：
[1] UNIV PISA, DIPARTIMENTO BIOMED SPERIMENTALE INFETT & PUBBL, I-56100 PISA, ITALY
[2] UNIV FERRARA, IST ZOOL, I-44100 FERRARA, ITALY
来源：
MARINE POLLUTION BULLETIN | 1990年 / 21卷 / 02期
关键词：
D O I：
10.1016/0025-326X(90)90191-A
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The micronucleus assay in gill tissue of the mussel Mytilus galloprovincialis has been developed in our Laboratory to assess the mutagenic activity of compounds present in marine environments. The sensitivity of the test was assessed by performing mutagenic treatment for 48 h with the two standard compounds vincristine (VCR) (0.005, 0.01, 0.02 mg l-1), and benzo(a)pyrene (BaP) (0.025, 0.075, 0.225, 0.675 mg l-1). Since both tested chemicals produced significant increases in the number of micronucleated cells, animals were directly exposed to marine waters: mussels grown in clean water (control sample) were transferred to polluted areas and then collected weekly. Micronuclei frequencies of sampled mussels were significantly higher than the value of the control group. © 1990.
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页码：74 / 80
页数：7
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