NUCLEOSIDES AND NUCLEOTIDES .117. A TRANSITION-STATE ANALOG IN PURINE NUCLEOTIDE BIOSYNTHESIS - THE DESIGN AND SYNTHESIS OF AN IMIDAZO[4,5-C]AZEPINE NUCLEOSIDE

被引：4

作者：

MINAKAWA, N ^{[1
]}

SASAKI, T ^{[1
]}

MATSUDA, A ^{[1
]}

机构：

[1] KANAZAWA UNIV,CANC RES INST,KANAZAWA,ISHIKAWA 920,JAPAN

来源：

关键词：

NUCLEOSIDE; IMIDAZO[4,5-C]AZEPINE NUCLEOSIDE; TRANSITION-STATE ANALOG; GMP SYNTHASE; ANTILEUKEMIC ACTIVITY;

D O I：

10.1016/S0960-894X(01)80873-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The design, synthesis, and antileukemic activity of 6-hydroxy-1-beta-D-ribofuranosyl-5,6-dihydroimidazo[4,5-c]azepin-4(1H)-one (4) are described.

引用

页码：183 / 186

页数：4