TRNA-DEPENDENT TRANSLATIONAL CONTROL OF IN VITRO HEMOGLOBIN SYNTHESIS

被引：46
作者：
ANDERSON, WF
GILBERT, JM
机构：
[1] Section on Human Biochemistry, Laboratory of Clinical Biochemistry, National Heart Institute, Bethesda
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 03期
关键词：
D O I：
10.1016/0006-291X(69)90586-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A tRNA-dependent rabbit reticulocyte cell-free system has been developed which is highly active in synthesizing hemoglobin. When unfractionated tRNA is used to supplement the system, approximately equal amounts of α and β chains are produced. When tRNA fractionated by Freon reverse phase chromatography is utilized, but with a specific portion deleted, α chain production is reduced to approximately 67% of the production of β chains. © 1969.
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页码：456 / &
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