A GUIDE TO THE INTERPRETATION OF SERUM PROSTATE-SPECIFIC ANTIGEN LEVELS

被引:46
作者
BUNTING, PS [1 ]
机构
[1] UNIV TORONTO, SUNNYBROOK HLTH SCI CTR, DEPT LAB MED, TORONTO, ON, CANADA
关键词
PROSTATE SPECIFIC ANTIGEN; PROSTATIC ACID PHOSPHATASE; REFERENCE RANGES; METABOLISM; ANALYSIS IN BLOOD; ANTIANDROGEN THERAPY; RADIATION THERAPY; RADICAL PROSTATECTOMY; INTRAINDIVIDUAL VARIATION; STAGE;
D O I
10.1016/0009-9120(95)91342-Z
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Objectives: To review the factors that af feet the concentration of prostate specific antigen (PSA) In the serum. Results: The discussion includes the structure of PSA; its distribution and metabolism; various analytical aspects of PSA measurements; the effects of clinical manipulations on PSA, including digital rectal examination, transrectal ultrasound, cystoscopy, biopsy and transurethral resection of the prostate; factors affecting PSA levels in health, in benign disease, and in prostate cancer; the effect of various treatments on PSA; and the issue of reference ranges. Conclusion: Laboratory staff and physicians must take many factors into consideration when interpreting PSA results.
引用
收藏
页码:221 / 241
页数:21
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