TOXAPHENE, A COMPLEX MIXTURE OF POLYCHLOROTERPENES AND A MAJOR INSECTICIDE, IS MUTAGENIC

被引：56
作者：
HOOPER, NK [1 ]
AMES, BN [1 ]
SALEH, MA [1 ]
CASIDA, JE [1 ]
机构：
[1] UNIV CALIF BERKELEY,DEPT ENTOMOL SCI,PESTICIDE CHEM & TOXICOL LAB,BERKELEY,CA 94720
来源：
SCIENCE | 1979年 / 205卷 / 4406期
关键词：
D O I：
10.1126/science.377495
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Toxaphene, the most widely used chlorinated insecticide, is mutagenic in the Salmonella test without requiring liver homogenate for activity. This insecticide is a complex mixture (more than 177 polychloroterpenes) with carcinogenic activity in rodents. Some but not all of the mutagenic components are easily separated from the insecticidal ingredients. Copyright © 1979 AAAS.
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页码：591 / 593
页数：3
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