ALPHA-2-ADRENOCEPTOR ANTAGONIST ACTIVITY MAY ACCOUNT FOR THE EFFECTS OF BUSPIRONE IN AN ANTICONFLICT TEST IN THE RAT

被引：83
作者：
GOWER, AJ [1 ]
TRICKLEBANK, MD [1 ]
机构：
[1] MERREL DOW RES CTR,F-67084 STRASBOURG,FRANCE
来源：
EUROPEAN JOURNAL OF PHARMACOLOGY | 1988年 / 155卷 / 1-2期
关键词：
D O I：
10.1016/0014-2999(88)90410-4
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：129 / 137
页数：9
相关论文
共 45 条
[1]  
BARRETT JE, 1986, J PHARMACOL EXP THER, V238, P1009
[2]   ALPHA-2-ADRENOCEPTOR AGONISTS INDUCE MYDRIASIS IN THE RAT BY AN ACTION WITHIN THE CENTRAL NERVOUS-SYSTEM [J].
BERRIDGE, TL ;
GADIE, B ;
ROACH, AG ;
TULLOCH, IF .
BRITISH JOURNAL OF PHARMACOLOGY, 1983, 78 (03) :507-515
[3]   DISPOSITION OF THE PSYCHOTROPIC-DRUGS BUSPIRONE, MJ-13805 AND PIRIBEDIL, AND OF THEIR COMMON ACTIVE METABOLITE 1-(2-PYRIMIDINYL)-PIPERAZINE IN THE RAT [J].
CACCIA, S ;
FONG, MH ;
GUISO, G .
XENOBIOTICA, 1985, 15 (10) :835-844
[4]   1-(2-PYRIMIDINYL)-PIPERAZINE AS ACTIVE METABOLITE OF BUSPIRONE IN MAN AND RAT [J].
CACCIA, S ;
CONTI, I ;
VIGANO, G ;
GARATTINI, S .
PHARMACOLOGY, 1986, 33 (01) :46-51
[5]   DISPOSITION AND METABOLISM OF BUSPIRONE AND ITS METABOLITE 1-(2-PYRIMIDINYL)-PIPERAZINE IN THE RAT [J].
CACCIA, S ;
MUGLIA, M ;
MANCINELLI, A ;
GARATTINI, S .
XENOBIOTICA, 1983, 13 (03) :147-153
[6]   YOHIMBINE INDUCED ANXIETY AND INCREASED NORADRENERGIC FUNCTION IN HUMANS - EFFECTS OF DIAZEPAM AND CLONIDINE [J].
CHARNEY, DS ;
HENINGER, GR ;
REDMOND, DE .
LIFE SCIENCES, 1983, 33 (01) :19-29
[7]   DEPRESSION OF EXPLORATORY ACTIVITY BY CLONIDINE IN RATS AS A MODEL FOR THE DETECTION OF RELATIVE PRESYNAPTIC AND POSTSYNAPTIC CENTRAL NORADRENERGIC RECEPTOR SELECTIVITY OF ALPHA-ADRENOLYTIC DRUGS [J].
DELINISTULA, A ;
BAUMANN, P ;
BUCH, O .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1979, 307 (02) :115-122
[8]  
Dourish C.T., 1987, BRAIN 5 HT1A RECEPTO, P261
[9]   SEROTONERGIC MECHANISMS IN THE BEHAVIORAL-EFFECTS OF BUSPIRONE AND GEPIRONE [J].
EISON, AS ;
EISON, MS ;
STANLEY, M ;
RIBLET, LA .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1986, 24 (03) :701-707
[10]   CLONIDINE - NEW RESEARCH IN PSYCHOTROPIC-DRUG PHARMACOLOGY [J].
FIELDING, S ;
LAL, H .
MEDICINAL RESEARCH REVIEWS, 1981, 1 (01) :97-123
12345