AN IMPROVEMENT ON COMMONLY USED TESTS IN BIOEQUIVALENCE ASSESSMENT

If equivalence of two treatments has to be proved by an experiment with normally distributed observations and fixed sample size, there are two usual methods. On the one hand, there is the double t test and, on the other hand, a test procedure suggested by Anderson and Hauck, which is uniformly more powerful than the first one but only capable of keeping asymptotically to the nominal level. Based on these two methods a new test is presented, which is uniformly more powerful than the double t test and also keeps the preassigned level.