IMPROVED SYNTHESIS OF QUINALDINES BY THE SKRAUP REACTION

被引：15

作者：

SONG, ZG

MERTZMAN, M

HUGHES, DL

机构：

[1] Department of Process Research, Merck & Co, Inc., Rahway, New Jersey

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1993年 / 30卷 / 01期

关键词：

D O I：

10.1002/jhet.5570300103

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of substituted quinaldines was synthesized with much improved yields from the reaction of crotonaldehyde and the corresponding anilines using either p-chloranil or 2,3-dichloro-1,4-naphthoquinone as the oxidant.

引用

页码：17 / 21

页数：5

共 5 条

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EISCH, JJ ;

DLUZNIEWSKI, T .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (06) :1269-1274

[2]

JONES G, 1977, CHEM HETEROCYCLIC 1, V32

[3] IMPROVEMENT IN DOEBNER-MILLER SYNTHESIS OF QUINALDINES [J].

LEIR, CM .

JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (05) :911-913

[4] QUINALDINE AND 4-HYDROXYQUINALDINE DERIVATIVES FROM META-CHLOROANILINE AND META-TOLUIDINE [J].

SPIVEY, AM ;

CURD, FHS .

JOURNAL OF THE CHEMICAL SOCIETY, 1949, (OCT) :2656-2662

[5] Improved syntheses of quinaldines and 3-alkyl quinolines [J].

Utermohlen, WP .

JOURNAL OF ORGANIC CHEMISTRY, 1943, 8 (06) :544-549

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