THE SPECTRUM OF LOW-MOLECULAR WEIGHT HOUSE DUST MITE (DERMATOPHAGOIDES-PTERONYSSINUS) ALLERGENS WITH EMPHASIS ON DER-P-II

被引：16

作者：

FORD, SA

TOVEY, ER

BALDO, BA

机构：

[1] ROYAL N SHORE HOSP,KOLLING INST MED RES,ST LEONARDS,NSW 2065,AUSTRALIA

[2] UNIV SYDNEY,DEPT MED,SYDNEY,NSW 2006,AUSTRALIA

来源：

CLINICAL AND EXPERIMENTAL ALLERGY | 1990年 / 20卷 / 01期

关键词：

D O I：

10.1111/j.1365-2222.1990.tb02771.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Analysis by protein blotting of sera from 96 different house dust mite‐allergic subjects revealed previously unrecognized complexity of low molecular weight (MW) (< 20 kD) IgE‐binding proteins in extracts of whole bodies of Dermatophagoides pteronyssinus. Of 11 different IgE‐binding components of MW < 20 kD identified, two (MW ∼ 16 kD and ∼ 15 kD), showed both a high frequency (88% and 49% respectively) and a high intensity of IgE‐binding. The ∼ 16 kD component, identified as allergen Der p II, showed the highest frequency of IgE antibody reactivity of any of the major D. pteronyssinus allergens including Der p I and Der p III. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：27 / 31

页数：5

共 17 条

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[4]

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