Risk of cytomegalovirus reactivation in patients with immune-mediated inflammatory diseases undergoing biologic treatment: a real matter?

被引：7

作者：

Mencarini, J. ^{[1
]}

Spinicci, M. ^{[1
]}

Bartalesi, F. ^{[2
]}

机构：

[1] Univ Florence, Infect Dis Unit, Florence, Italy

[2] Careggi Hosp, Infect & Trop Dis Div, Largo Brambilla 3, I-50314 Florence, Italy

来源：

REUMATISMO | 2016年 / 68卷 / 03期

关键词：

Cytomegalovirus; screening; biological agents; inflammatory diseases;

D O I：

10.4081/reumatismo.2016.897

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The use of biological agents has grown exponentially in immune-mediated inflammatory diseases (IMID), often achieving a good control of disease progression and improving patients' quality of life. However, their use resulted in an increased risk of adverse events, including reactivation of chronic/latent infectious diseases. As for the risk of Cytomegalovirus (CMV) reactivation, very few data are available. We reviewed the literature reporting cases of CMV infection in IMID patients during biological therapy. Although the risk of CMV reactivation cannot be excluded, we concluded that there is no evidence to warrant CMV screening before starting a biological agent.

引用

收藏

页码：144 / 147

页数：4

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