EFFECT OF PARTIAL-PRESSURE ON SOLUBILITY OF ISOFLURANE IN BLOOD

被引：0

作者：

XIE, GM ^{[1
]}

LAUBER, R ^{[1
]}

ZBINDEN, AM ^{[1
]}

机构：

[1] UNIV HOSP BERN,INST ANAESTHESIOL & INTENS CARE,CH-3010 BERN,SWITZERLAND

来源：

CHINESE MEDICAL JOURNAL | 1995年 / 108卷 / 09期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effect of partial pressure of isoflurane on its solubility in blood of different haematocrit was determined at different isoflurane partial pressures, using a syringe-flask method and gas chromatography with blood from one donor. The solubility of isoflurane decreased with increasing blood haematocrit (39.5%, 51.9% and 61.9%) and isoflurane partial pressure from 1 MAC to 4 MAC. The solubility in 50% and 60% haematocrit blood at 2, 3 and 4 MAC was significantly different from the solubility in normal blood at 1 MAC (P<0.05). We conclude that the solution of isoflurane in blood (especially in high haematocrit blood) does not obey Henry's law.

引用

页码：665 / 668

页数：4

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