STRUCTURAL AND FUNCTIONAL-ORGANIZATION OF THE NUCLEAR-ENVELOPE

被引：114
作者：
GOLDBERG, MW [1 ]
ALLEN, TD [1 ]
机构：
[1] PATERSON INST CANC RES,MANCHESTER M20 9BX,LANCS,ENGLAND
来源：
CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 03期
关键词：
D O I：
10.1016/0955-0674(95)80083-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The double-membrane nuclear envelope is punctuated by pores where the two membranes are joined. These pores are stabilized by the elaborate nuclear pore complex, which is anchored to the inner membrane by the nuclear lamina, as well as to other nuclear and cytoskeletal structures. Recent experiments have identified proteins involved in the stability of this organization as well as in the function of the nuclear pore complex, which we relate here to newer aspects of nuclear envelope structure.
引用
收藏
页码：301 / 309
页数：9
相关论文
共 55 条
[1]  
Fabre, Hurt, Nuclear transport, Curr Opin Cell Biol, 6, pp. 335-342, (1994)
[2]  
Powers, Forbes, Cytosolic factors in nuclear transport: what's important?, Cell, 79, pp. 931-934, (1994)
[3]  
Wiese, Wilson, Nuclear membrane dynamics, Curr Opin Cell Biol, 5, pp. 387-394, (1993)
[4]  
Pante, Aebi, Towards understanding the three-dimensional structure of the nuclear pore complex at the molecular level, Current Opinion in Structural Biology, 4, pp. 187-196, (1994)
[5]  
Rout, Wente, Pores for thought: nuclear pore complex proteins, Trends in Cell Biology, 4, pp. 357-365, (1994)
[6]  
Hutchison, Bridger, Cox, Kill, Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication, J Cell Sci, 107, pp. 3259-3269, (1994)
[7]  
Aebi, Cohn, Buhle, Gerace, The nuclear lamina is a meshwork of intermediate-type filaments, Nature, 323, pp. 560-564, (1986)
[8]  
Goldberg, Allen, The nuclear pore complex: three-dimensional surface structure revealed by field emission, in-lens scanning electron microscopy with underlying structure uncovered by proteolysis, J Cell Sci, 106, pp. 261-274, (1993)
[9]  
Hennekes, Nigg, The role of isoprenylation in membrane attachment of nuclear lamins, J Cell Sci, 107, pp. 1019-1029, (1994)
[10]  
Gerace, Foisner, Integral membrane proteins and dynamic organisation of the nuclear envelope, Trends Cell Biol, 4, pp. 127-131, (1994)
123456