SYNTHESIS AND XANTHINE-OXIDASE INHIBITORY ACTIVITY OF PYRAZOLO[3,4-D]PYRIMIDINES

被引：46

作者：

KOBAYASHI, S ^{[1
]}

机构：

[1] TAKEDA CHEM IND LTD, CENT RES DIV, CHEM RES LABS, HIGASHIYODOGAWA, OSAKA 532, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1973年 / 21卷 / 05期

关键词：

D O I：

10.1248/cpb.21.941

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：941 / 951

页数：11

共 35 条

[1] IRREVERSIBLE ENZYME INHIBITORS .125. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF XANTHINE OXIDASE DERIVED FROM ARYLPURINES AND PYRAZOLO[3,4-D]PYRIMIDINES BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
KOZMA, JA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) : 656 - &
[2] IRREVERSIBLE ENZYME INHIBITORS .156. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF XANTHINE OXIDASE DERIVED FROM 9-(ACYLAMIDOPHENYL)GUANINES SUBSTITUTED WITH A TERMINAL SULFONYL FLUORIDE
BAKER, BR
WOOD, WF
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) : 211 - &
[3] IRREVERSIBLE ENZYME INHIBITORS .122. ON NATURE AND DIMENSIONS OF HYDROPHOBIC BONDING REGION OF GUANINE DEAMINASE AND XANTHINE OXIDASE
BAKER, BR
WOOD, WF
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) : 644 - &
[4] IRREVERSIBLE ENZYME INHIBITORS .126. HYDROCARBON INTERACTION WITH XANTHINE OXIDASE BY PHENYL SUBSTITUENTS ON PURINES AND PYRAZOLO[3,4-D]PYRIMIDINES
BAKER, BR
WOOD, WF
KOZMA, JA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) : 661 - &
[5] IRREVERSIBLE ENZYME INHIBITORS .93. HYDROPHOBIC BONDING TO XANTHINE OXIDASE BY SOME PHENYLPURINES
BAKER, BR
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1967, 56 (08) : 959 - &
[6] IRREVERSIBLE ENZYME INHIBITORS .147. CANDIDATE ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF XANTHINE OXIDASE DERIVED FROM 9-(P-ACYLAMIDOALKOXYPHENYL)GUANINES BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
WOOD, WF
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) : 214 - &
[7] IRREVERSIBLE ENZYME INHIBITORS .92. INHIBITION OF XANTHINE OXIDASE BY SOME PURINES AND PYRIMIDINES
BAKER, BR
HENDRICKSON, JL
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1967, 56 (08) : 955 - +
[8] BALLIO A., 1960, GAZZETTA CHIM ITAL, V90, P501
[9] INFLUENCE OF MONO- AND DIMETHYLAMINO SUBSTITUENTS ON ENZYMIC OXIDATION OF PURINES
BERGMANN, F
UNGAR, H
LEVIN, G
KWIETNYG.H
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1961, 47 (01) : 1 - &
[10] CARTER CE, 1956, J BIOL CHEM, V223, P139

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