Reversible deafness and blindness in a patient with cryptococcal meningitis in Tanzania

被引:3
作者
Douglas-Vail, Matt [1 ]
Bechamp, Taylor [1 ]
Gohal, Simran [1 ]
Soegtrop, Robert [1 ]
Vitali, Sarah [1 ]
Rugemalila, Joan [2 ]
Stone, Neil R. H. [3 ]
机构
[1] Western Univ, Schulich Sch Med & Dent, London, ON, Canada
[2] Muhimbili Natl Hosp, Dar Es Salaam, Tanzania
[3] Univ London, Inst Infect & Immun, St Georges, Cranmer Terrace, London WC1E 7HU, England
基金
英国惠康基金;
关键词
HIV; Cryptococcal meningitis; mycology; opportunistic infections; fluconazole;
D O I
10.4081/idr.2015.6173
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Cryptococcal meningitis is a common and devastating complication of advanced HIV and is most prevalent in low resource settings in sub Saharan Africa. Raised intracranial pressure is one of the hallmarks of the disease, which can lead to visual and hearing loss and ultimately death. We present the case of a patient with visual and hearing impairment secondary to Cryptococcal meningitis successfully managed by serial cerebrospinal fluid drainage. This case highlights some of the challenges of managing this severe opportunistic infection in a low resource setting.
引用
收藏
页码:74 / 76
页数:3
相关论文
共 19 条
  • [1] Standardized Electrolyte Supplementation and Fluid Management Improves Survival During Amphotericin Therapy for Cryptococcal Meningitis in Resource-Limited Settings
    Bahr, Nathan C.
    Rolfes, Melissa A.
    Musubire, Abdu
    Nabeta, Henry
    Williams, Darlisha A.
    Rhein, Joshua
    Kambugu, Andrew
    Meya, David B.
    Boulware, David R.
    [J]. OPEN FORUM INFECTIOUS DISEASES, 2014, 1 (02):
  • [2] Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures
    Bicanic, Tihana
    Brouwer, Annemarie E.
    Meintjes, Graeme
    Rebe, Kevin
    Limmathurotsakul, Direk
    Chierakul, Wirongrong
    Teparrakkul, Praprit
    Loyse, Angela
    White, Nicholas J.
    Wood, Robin
    Jaffar, Shabbar
    Harrison, Thomas
    [J]. AIDS, 2009, 23 (06) : 701 - 706
  • [3] Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis
    Boulware, David R.
    Meya, David B.
    Muzoora, Conrad
    Rolfes, Melissa A.
    Hullsiek, Katherine Huppler
    Musubire, Abdu
    Taseera, Kabanda
    Nabeta, Henry W.
    Schutz, Charlotte
    Williams, Darlisha A.
    Rajasingham, Radha
    Rhein, Joshua
    Thienemann, Friedrich
    Lo, Melanie W.
    Nielsen, Kirsten
    Bergemann, Tracy L.
    Kambugu, Andrew
    Manabe, Yukari C.
    Janoff, Edward N.
    Bohjanen, Paul R.
    Meintjes, Graeme
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (26) : 2487 - 2498
  • [4] Relevance of intracranial hypertension control in the management of Cryptococcus neoformans meningitis related to AIDS
    de Vedia, L.
    Arechavala, A.
    Calderon, M. I.
    Maiolo, E.
    Rodriguez, A.
    Lista, N.
    Di Virgilio, E.
    Cisneros, J. C.
    Prieto, R.
    [J]. INFECTION, 2013, 41 (06) : 1073 - 1077
  • [5] ELEVATED CEREBROSPINAL-FLUID PRESSURES IN PATIENTS WITH CRYPTOCOCCAL MENINGITIS AND ACQUIRED-IMMUNODEFICIENCY-SYNDROME
    DENNING, DW
    ARMSTRONG, RW
    LEWIS, BH
    STEVENS, DA
    [J]. AMERICAN JOURNAL OF MEDICINE, 1991, 91 (03) : 267 - 272
  • [6] Duggan Joan, 2012, J Int Assoc Physicians AIDS Care (Chic), V11, P283, DOI 10.1177/1545109712448537
  • [7] TEMPORAL BONE HISTO-PATHOLOGY IN DEAFNESS DUE TO CRYPTOCOCCAL MENINGITIS
    HARADA, T
    SANDO, I
    MYERS, EN
    [J]. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1979, 88 (05) : 630 - 636
  • [8] KEANE JR, 1993, J CLIN NEURO-OPHTHAL, V13, P124
  • [9] Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal
    Loyse, Angela
    Dromer, Francoise
    Day, Jeremy
    Lortholary, Olivier
    Harrison, Thomas S.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (11) : 2435 - 2444
  • [10] Cryptococcal Meningitis Management in Tanzania With Strict Schedule of Serial Lumber Punctures Using Intravenous Tubing Sets: An Operational Research Study
    Meda, John
    Kalluvya, Samuel
    Downs, Jennifer A.
    Chofle, Awilly A.
    Seni, Jeremiah
    Kidenya, Benson
    Fitzgerald, Daniel W.
    Peck, Robert N.
    [J]. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2014, 66 (02) : E31 - E36