A GENERAL SCHEME FOR INCORPORATING NONNATURAL FUNCTIONALITY INTO PEPTIDES

被引：7

作者：

CUENOUD, B ^{[1
]}

SCHEPARTZ, A ^{[1
]}

机构：

[1] YALE UNIV,DEPT CHEM,NEW HAVEN,CT 06511

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 28期

关键词：

LEUCINE ZIPPER; DNA-BINDING; CHEMICAL SYNTHESIS; ACTIVATOR PROTEIN; REPORTER GROUPS; GCN4; YEAST; RNA; SPECIFICITY; ATTACHMENT;

D O I：

10.1016/S0040-4039(00)92697-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe a convergent synthesis of DELTA-GCN4(229-248)-terpyridyl 1, which contains a terpyridyl ligand attached covalently through a disulfide bond to the proposed DNA binding domain of the yeast transcriptional activator protein GCN4.

引用

页码：3325 / 3328

页数：4

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