METHYLMALONYL COA AS AN ABNORMAL SUBSTRATE FOR DELTA-AMINOLEVULINIC ACID SYNTHETASE

被引：5
作者：
GOMPERTZ, D
机构：
[1] Department of Medicine, Royal Postgraduate Medical School, Department of Biochemistry, London
来源：
CLINICA CHIMICA ACTA | 1969年 / 25卷 / 03期
关键词：
D O I：
10.1016/0009-8981(69)90209-5
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The effect of methylmalonyl CoA on δ-aminolevulinic acid synthetase has been investigated. Methylmalonyl CoA has been shown to act as an abnormal substrate for this enzyme but does not inhibit the formation of δ-aminolevulinic acid from succinyl CoA. The product of the condensation of methylmalonyl CoA and glycine appears to be an aminoketoacid and it is suggested that it is a chain isomer of δ-aminolevulinic acid. © 1969.
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页码：459 / &
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