CHROMOSOME INSITU SUPPRESSION HYBRIDIZATION IN CLINICAL CYTOGENETICS

被引：16

作者：

HULTEN, MA

GOULD, CP

GOLDMAN, ASH

WATERS, JJ

机构：

[1] West Midlands Regional Genetics Service, East Birmingham Hospital, Bordesley Green East

来源：

JOURNAL OF MEDICAL GENETICS | 1991年 / 28卷 / 09期

关键词：

D O I：

10.1136/jmg.28.9.577

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The use of chromosome in situ suppression hybridisation with whole chromosome libraries has previously been reported by various research laboratories to be an effective method of identifying specific human chromosomal material. As a clinical cytogenetic service laboratory we have used the technique as a complement to diagnosis by classical chromosome banding. In three examples of structural rearrangements the potential use of the 'chromosome painting' method is assessed for its ability to enhance the routine cytogenetic service currently available.

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页码：577 / 582

页数：6

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