COMPARISON OF THE COMBINED EFFECTS OF ATROPINE AND NEOSTIGMINE WITH ATROPINE AND EDROPHONIUM ON THE LOWER ESOPHAGEAL SPHINCTER

被引：4

作者：

HEIJKE, SAM ^{[1
]}

SMITH, G ^{[1
]}

KEY, A ^{[1
]}

机构：

[1] UNIV LEICESTER,LEICESTER ROYAL INFIRM,DEPT ANAESTHESIA,LEICESTER LE1 5WW,ENGLAND

来源：

ANAESTHESIA | 1991年 / 46卷 / 08期

关键词：

ANTAGONISTS; NEUROMUSCULAR RELAXANTS; EDROPHONIUM; NEOSTIGMINE; GASTROINTESTINAL TRACT; ESOPHAGUS; COMPLICATIONS; REGURGITATION;

D O I：

10.1111/j.1365-2044.1991.tb09708.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

In two groups (n = 11) of healthy patients, we have measured gastric, lower oesophageal and barrier pressures before and after antagonism of neuromuscular block during anaesthesia with nitrous oxide and isoflurane. In one group, atropine 1.2 mg and neostigmine 2.5 mg were given and in the second group atropine 0.6 mg with edrophonium 1 mg/kg. One minute after administration of the reversal agents, there was a significantly greater reduction in barrier pressures in the neostigmine and atropine group than in the edrophonium and atropine group, but subsequently, there was no significant difference between the two groups. We conclude that there is no clinical difference between the two reversal mixtures in terms of the risk of regurgitation in the immediate period after reversal. Copyright © 1991, Wiley Blackwell. All rights reserved

引用

页码：628 / 631

页数：4

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