Nivolumab-induced severe acute kidney injury with a long latent phase in a patient with non-small-cell lung cancer: A case report

被引：9

作者：

Uchida, Naohiro ^{[1
]}

Tsuji, Seijiro ^{[2
]}

Fujita, Kohei ^{[1
]}

Koizumi, Mitsuteru ^{[2
]}

Moriyoshi, Koki ^{[3
]}

Mio, Tadashi ^{[1
]}

机构：

[1] Natl Hosp Org Kyoto Med Ctr, Ctr Resp Dis, Div Resp Med, Kyoto, Japan

[2] Natl Hosp Org Kyoto Med Ctr, Dept Nephrol, Kyoto, Japan

[3] Natl Hosp Org Kyoto Med Ctr, Div Clin Pathol, Kyoto, Japan

来源：

CLINICAL CASE REPORTS | 2018年 / 6卷 / 11期

关键词：

acute kidney injury; immune checkpoint inhibitors; immune-related adverse event; nivolumab;

D O I：

10.1002/ccr3.1848

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the treatment of immunotherapy with immune checkpoint inhibitors, we often experience immune-related adverse event which manifest most frequently as a skin disorder, and very rarely as a renal disorder. In our manuscript, we report the case of a 71-year-old man with nivolumab-induced severe acute kidney injury (AKI) in which the time from treatment initiation to the onset of AKI was the longest among the previously reported cases (377 days). Prolonged follow-up is therefore warranted to detect late-onset AKI.

引用

页码：2185 / 2188

页数：4

共 6 条

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