STRUCTURAL AND DYNAMIC DIFFERENCES BETWEEN NORMAL AND TRANSFORMING N-RAS GENE-PRODUCTS - A P-31 AND ISOTOPE-EDITED H-1-NMR STUDY

被引:24
作者
CAMPBELLBURK, S [1 ]
机构
[1] BRANDEIS UNIV,DEPT BIOCHEM,WALTHAM,MA 02254
关键词
D O I
10.1021/bi00450a035
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:9478 / 9484
页数:7
相关论文
共 42 条
[1]  
BARBACID M, 1987, ANNU REV BIOCHEM, V56, P799
[2]   CORRELATION OF PROTON AND N-15 CHEMICAL-SHIFTS BY MULTIPLE QUANTUM NMR [J].
BAX, A ;
GRIFFEY, RH ;
HAWKINS, BL .
JOURNAL OF MAGNETIC RESONANCE, 1983, 55 (02) :301-315
[3]   AMINO-ACID SUBSTITUTIONS AT CODON-13 OF THE N-RAS ONCOGENE IN HUMAN ACUTE MYELOID-LEUKEMIA [J].
BOS, JL ;
TOKSOZ, D ;
MARSHALL, CJ ;
VERLAANDEVRIES, M ;
VEENEMAN, GH ;
VANDEREB, AJ ;
VANBOOM, JH ;
JANSSEN, JWG ;
STEENVOORDEN, ACM .
NATURE, 1985, 315 (6022) :726-730
[4]  
CAMPBELLBURK S, 1989, P NATL ACAD SCI USA, V86, P817
[5]   ACTIVATION OF KI-RAS 2 GENE IN HUMAN-COLON AND LUNG CARCINOMAS BY 2 DIFFERENT POINT MUTATIONS [J].
CAPON, DJ ;
SEEBURG, PH ;
MCGRATH, JP ;
HAYFLICK, JS ;
EDMAN, U ;
LEVINSON, AD ;
GOEDDEL, DV .
NATURE, 1983, 304 (5926) :507-513
[6]  
COHN M, 1979, NMR BIOCH
[7]   3-DIMENSIONAL STRUCTURE OF AN ONCOGENE PROTEIN - CATALYTIC DOMAIN OF HUMAN C-H-RAS P21 [J].
DEVOS, AM ;
TONG, L ;
MILBURN, MV ;
MATIAS, PM ;
JANCARIK, J ;
NOGUCHI, S ;
NISHIMURA, S ;
MIURA, K ;
OHTSUKA, E ;
KIM, SH .
SCIENCE, 1988, 239 (4842) :888-893
[8]   ACTIVATION OF RAS GENES IN HUMAN-TUMORS DOES NOT AFFECT LOCALIZATION, MODIFICATION, OR NUCLEOTIDE BINDING-PROPERTIES OF P21 [J].
FINKEL, T ;
DER, CJ ;
COOPER, GM .
CELL, 1984, 37 (01) :151-158
[9]   ATP-BINDING SITE OF ADENYLATE KINASE - MECHANISTIC IMPLICATIONS OF ITS HOMOLOGY WITH RAS-ENCODED P21, F1-ATPASE, AND OTHER NUCLEOTIDE-BINDING PROTEINS [J].
FRY, DC ;
KUBY, SA ;
MILDVAN, AS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (04) :907-911
[10]   MONOCLONAL-ANTIBODIES TO THE P21 PRODUCTS OF THE TRANSFORMING GENE OF HARVEY MURINE SARCOMA-VIRUS AND OF THE CELLULAR RAS GENE FAMILY [J].
FURTH, ME ;
DAVIS, LJ ;
FLEURDELYS, B ;
SCOLNICK, EM .
JOURNAL OF VIROLOGY, 1982, 43 (01) :294-304