INDOMETHACIN INCREASES ABORTIFACIENT EFFECT OF PGE2 IN MAN

被引：8

作者：

PIOTROWSKI, J ^{[1
]}

BASTA, A ^{[1
]}

KLIMCZYK, K ^{[1
]}

MALOLEPSZY, A ^{[1
]}

DLUZNIEWSKA, M ^{[1
]}

SPLAWINSKI, JA ^{[1
]}

机构：

[1] COPERNICUS MED ACAD,DEPT PHARMACOL,PL-31501 CRACOW,POLAND

来源：

PROSTAGLANDINS | 1979年 / 17卷 / 03期

关键词：

D O I：

10.1016/S0090-6980(79)80013-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Results of this study indicate that pretreatment with indomethacin significantly increases the abortifacient effect of an intravenous infusion of PGE2 in patients admitted for abortion as a result of fetal death in utero. Indomethacin pretreatment shortened the duration of PGE2-induced abortion in primigravid and multigravid groups of patients by about 4 and 2 hours respectively. When primigravid and multigravid groups were combined, the dose of PGE2 needed for complete delivery decreases in the indomethacin-treated group by 39.9%. © 1979.

引用

页码：451 / 459

页数：9

共 28 条

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