QUANTITATIVE DETERMINATION OF FURAZOLIDONE AND NIFUROXIME IN A WATER-SOLUBLE SUPPOSITORY BASE

被引：7

作者：

BOICE, R

SEIDMAN, M

SOUTHWORTH, BC

机构：

[1] Quality Control Department, The Norwich Pharmacal Co, Norwich, New York

[2] Xerox Corp, Pasadena, California, 91 107

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 12期

关键词：

Furazolidone and nifuroxime suppositories—analysis; IR spectrophotometry—identity; Spectrodensitometry—TLC spot analysis; TLC—separation;

D O I：

10.1002/jps.2600581223

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A thin‐layer chromatographic procedure has been developed for the analysis of furazolidone and nifuroxime in suppositories. The sample is dissolved in a suitable solvent and chromatographed. The separated nitrofurans are then compared to respective standards densitometrically. The coefficient variation is 2.4% for furazolidone and 2.7% for nifuroxime. Evidence is presented to indicate that only the intact compounds are measured. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：1527 / +

页数：1

共 18 条

[1] THIN-LAYER CHROMATOGRAPHY OF DRUGS IN MEDICATED FEEDS [J].