NEW ENANTIOSELECTIVE APPROACH TO ALPHA-ALLOKAINOIDS BY MICHAEL ADDITION TO CHIRAL 4-SUBSTITUTED 2,3-DIDEHYDROPROLINATE

被引：25

作者：

EZQUERRA, J

ESCRIBANO, A

RUBIO, A

REMUINAN, MJ

VAQUERO, JJ

机构：

[1] CTR INVEST LILLY, E-28130 MADRID, SPAIN

[2] UNIV ALCALA DE HENARES, DEPT QUIM ORGAN, E-28871 ALCALA DE HENARES, SPAIN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 34期

关键词：

D O I：

10.1016/0040-4039(95)01165-E

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(-) and (+) alpha-Allokainoids hydrochlorides 3 and 4 were obtained by hydrolysis of the corresponding Michael adducts resulting from the addition of diethyl malonate to chiral N-urethane protected ethyl 4-benzyl-2,3-didehydroprolinates 9 and 13 respectively.

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页码：6149 / 6152

页数：4

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