A RELIABILITY STUDY OF SLEDAI - A DISEASE-ACTIVITY INDEX FOR SYSTEMIC LUPUS-ERYTHEMATOSUS

被引:0
|
作者
HAWKER, G
GABRIEL, S
BOMBARDIER, C
GOLDSMITH, C
CARON, D
GLADMAN, D
机构
[1] WELLESLEY COLL HOSP, DEPT MED, DIV RHEUMATOL, TORONTO M4Y 1J3, ONTARIO, CANADA
[2] MAYO CLIN & MAYO FDN, DEPT MED, DIV RHEUMATOL, ROCHESTER, MN 55905 USA
[3] MCMASTER UNIV, DEPT CLIN EPIDEMIOL & BIOSTAT, HAMILTON L8S 4L8, ONTARIO, CANADA
[4] WELLESLEY COLL HOSP, CLIN EPIDEMIOL UNIT, TORONTO M4Y 1J3, ONTARIO, CANADA
关键词
LUPUS DISEASE ACTIVITY; SLEDAI; OUTCOME MEASURES;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
SLEDAI, a disease activity index for systemic lupus erythematosus (SLE) has been validated against other such indices and its reliability has been shown by specialists in SLE. To assess its reliability among less experienced clinicians, we conducted a reliability study 3 rheumatology trainees and 9 patients with SLE according to a Latin square design. SLEDAI easily distinguished between patients (p = 0.0009), and physician variability was not statistically significant (p = 0.27). Inter and intraobserver agreement were 78.7 and 98.0%, respectively. SLEDAI was thus shown to be a reliable instrument among less experienced observers for the assessment of disease activity in SLE.
引用
收藏
页码:657 / 660
页数:4
相关论文
共 50 条
  • [21] Assessment Of disease activity in Systemic Lupus Erythematosus: Lights and shadows
    Ceccarelli, Fulvia
    Perricone, Carlo
    Massaro, Laura
    Cipriano, Enrica
    Alessandri, Cristiano
    Spinelli, Francesca Romana
    Valesini, Guido
    Conti, Fabrizio
    AUTOIMMUNITY REVIEWS, 2015, 14 (07) : 601 - 608
  • [22] Hyponatremia in systemic lupus erythematosus patients: Relation to disease activity and fatigue
    El-Badawy, Mohja A.
    El-Mahdi, Amira R.
    El-Sherbiny, Dalia A.
    Bawady, Somia A. H.
    EGYPTIAN RHEUMATOLOGIST, 2019, 41 (04) : 283 - 287
  • [23] Burden of autoantibodies and association with disease activity and damage in systemic lupus erythematosus
    Touma, Z.
    Gladman, D. D.
    Tulloch-Reid, D.
    Toloza, S. M.
    Ibanez, D.
    Fortin, P. R.
    Urowitz, M. B.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2010, 28 (04) : 525 - 531
  • [24] Cytokine production, serum levels and disease activity in systemic lupus erythematosus
    Gröndal, G
    Gunnarsson, I
    Rönnelid, J
    Rogberg, S
    Klareskog, L
    Lundberg, I
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2000, 18 (05) : 565 - 570
  • [25] Interleukin-6 and disease activity in childhood systemic lupus erythematosus
    Satria, Cahya Dewi
    Kurniati, Nia
    Muktiarti, Dina
    PAEDIATRICA INDONESIANA, 2023, 63 (06) : 456 - 463
  • [26] Digital vasculitis in systemic lupus erythematosus: a minor manifestation of disease activity?
    Gomes, C.
    Carvalho, J. F.
    Borba, E. F.
    Borges, C. T. L.
    Vendramini, M. B.
    Bueno, C.
    Costa, L. P.
    Bonfa, E.
    LUPUS, 2009, 18 (11) : 990 - 993
  • [27] Cognitive dysfunction in systemic lupus erythematosus in relation to disease activity and damage
    Dorman, Guido
    Micelli, Marina
    Cosentino, Vanesa
    Ottone, Laura
    Rosa Nunez, Maria
    Mangone, Carlos
    Rey, Raul C.
    Kerzberg, Eduardo
    Genovese, Osvaldo
    MEDICINA-BUENOS AIRES, 2017, 77 (04) : 257 - 260
  • [28] A cross-sectional study on the association of anxiety and depression with the disease activity of systemic lupus erythematosus
    Liao, Jiafen
    Kang, Jin
    Li, Fen
    Li, Qi
    Wang, Jia
    Tang, Qi
    Mao, Ni
    Li, Shu
    Xie, Xi
    BMC PSYCHIATRY, 2022, 22 (01)
  • [29] A cross-sectional study on the association of anxiety and depression with the disease activity of systemic lupus erythematosus
    Jiafen Liao
    Jin Kang
    Fen Li
    Qi Li
    Jia Wang
    Qi Tang
    Ni Mao
    Shu Li
    Xi Xie
    BMC Psychiatry, 22
  • [30] A novel lupus activity index accounting for glucocorticoids: SLEDAI-2K glucocorticoid index
    Touma, Zahi
    Gladman, Dafna D.
    Su, Jiandong
    Anderson, Nicole
    Urowitz, Murray B.
    RHEUMATOLOGY, 2018, 57 (08) : 1370 - 1376