STRUCTURAL-ANALYSIS OF 5 NEW MONOSIALYLATED OLIGOSACCHARIDES FROM HUMAN-MILK

被引：36
作者：
GRONBERG, G
LIPNIUNAS, P
LUNDGREN, T
LINDH, F
NILSSON, B
机构：
[1] BIOCARB TECHNOL AB,S-22370 LUND,SWEDEN
[2] UNIV LUND,DEPT CARBOHYDRATE CHEM,S-22370 LUND,SWEDEN
来源：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1992年 / 296卷 / 02期
关键词：
D O I：
10.1016/0003-9861(92)90616-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The total monosialylated oligosaccharide fraction from pooled human milk was isolated by gel filtration and ion-exchange chromatography. Further separation by HPLC using a mobile phase containing an ion-pairing reagent of triethylamine gave five new monosialylated oligosaccharides. Structural analysis was carried out by chemical analyses, fast atom bombardment mass spectrometry, and 500-MHz NMR spectroscopy. Combined structural data revealed the following new structures:. © 1992.
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页码：597 / 610
页数：14
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