HIGH-AFFINITY KAINATE AND DOMOATE RECEPTORS IN RAT-BRAIN

被引：128
|
作者：
LOMELI, H [1 ]
WISDEN, W [1 ]
KOHLER, M [1 ]
KEINANEN, K [1 ]
SOMMER, B [1 ]
SEEBURG, PH [1 ]
机构：
[1] UNIV HEIDELBERG,CTR MOLEC BIOL,MOLEC NEUROENDOCRINOL LAB,INF 282,W-6900 HEIDELBERG,GERMANY
来源：
FEBS LETTERS | 1992年 / 307卷 / 02期
关键词：
GLUTAMATE RECEPTOR; HIGH-AFFINITY KAINATE BINDING; DOMOATE;
D O I：
10.1016/0014-5793(92)80753-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Mammalian brain expresses receptors which bind the potent neurotoxins, kainate and domoate, with high affinity, and which form a subclass of ionotropic glutamate receptors. A new member of these receptors, expressed in both adult and embryonic CNS is compared in its ligand binding properties to its closely sequence-related homologs.
引用
收藏
页码：139 / 143
页数：5
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