ENHANCEMENT OF PERIPHERAL-NERVE REGENERATION

被引：165

作者：

SECKEL, BR

机构：

[1] Department of Plastic and Reconstructive Surgery, Lahey Clinic Medical Center, Burlington, Massachusetts

来源：

MUSCLE & NERVE | 1990年 / 13卷 / 09期

关键词：

entubulation nerve repair; nerve growth factor; nerve guide; nerve regeneration; nerve regeneration chamber; nerve repair; neural regeneration; neuronotrophic factors; neurotropic factors;

D O I：

10.1002/mus.880130904

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Numerous factors eternal to the nerve cell can support and enhance nerve regeneration after injury. The definition of these factors and the elucidation of their mechanisms of action are the central goals of much contemporary neurobiologic research. This research will hopefully lead to the discovery of factors that will prove to be therapeutically beneficial for patients with either peripheral nervous system (PNS) injury or central nervous system (CNS) injury. This article reviews the biology of the regeneration response of the nerve to injury and discusses many of the factors that enhance nerve growth. Finally, the nerve guide or nerve regeneration chamber model for the evaluation of putative nerve regeneration enhancing agents in vivo is also discussed. Copyright © 1990 John Wiley & Sons, Inc.

引用

页码：785 / 800

页数：16

共 151 条

[21] ACIDIC FIBROBLAST GROWTH-FACTOR ENHANCES PERIPHERAL-NERVE REGENERATION INVIVO [J].