Systemic candidosis and antifungal azole agents

Systemic candidosis, the frequency of which increased, are associated with a high mortality rate, Triazole compounds, well tolerated, are useful for prophylaxis in neutropenia, with a good efficacy, For the treatment, trials do not show any significant difference between Fluconazole effects and those of Amphotericin B. Triazole agents are better tolerated than Amphotericin B under its usual galenic form. New triazole compounds still under development, seem to be full of promise.