OXIDATIVE ADDITION OF AZIDE ANION TO TRIISOPROPYLSILYL ENOL ETHERS - SYNTHESIS OF ALPHA-AZIDO KETONES AND 2-AMINO(METHOXYCARBONYL)ALK-2-EN-1-ONES

被引：27
作者：
MAGNUS, P
BARTH, L
机构：
[1] Department of Chemistry and Biochemistry, University of Texas at Austin, Austin
来源：
TETRAHEDRON | 1995年 / 51卷 / 41期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0040-4020(95)00681-W
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of triisopropylsilyl enol ethers with eerie ammonium nitrate/sodium azide at -20 degrees C in acetonitrile gives alpha-azido ketones in average to good yields (50-80%). Subsequent conversion of the alpha-azido ketones into 2-amino(methoxycarbonyl)cycloalk-2-en-1-ones is described.
引用
收藏
页码：11075 / 11086
页数：12
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