Resistant Thyrotoxicosis due to Graves' Disease in Pregnancy: Case Report and Review of the Literature

被引：4

作者：

Linardi, Anastasia ^{[1
]}

Michou, Ekaterini ^{[1
]}

Ilias, Ioannis ^{[1
]}

Petychaki, Foteini ^{[1
]}

Kakoulidis, Ioannis ^{[1
]}

Pappa, Athina ^{[1
]}

Koukkou, Eftychia ^{[1
]}

机构：

[1] E Venizelou Hosp, Dept Endocrinol Diabet & Metab, Athens, Greece

来源：

CUREUS | 2018年 / 10卷 / 08期

关键词：

female; humans; hyperthyroidism; pregnancy; complications; thyroid diseases;

D O I：

10.7759/cureus.3232

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effective management of Graves' disease (GD) during pregnancy is crucial for maternal and neonatal well-being. Conventional treatment of GD during pregnancy includes antithyroid drugs (ATDs) and surgery, ideally during the second trimester. We report a 27-year-old woman with GD and we present the course of GD during her three consecutive pregnancies. During the first pregnancy, thyrotoxicosis was successfully treated with low doses of antithyroid drugs; in the second pregnancy, thyrotoxicosis was only controlled at the third trimester; while in the third pregnancy, our patient presented with treatment-resistant thyrotoxicosis, which was finally managed with corticosteroids in adjunction with ATDs. Although hyperthyroid, the patient maintained her fertility. Resistance to ATD is a rare condition and in our case was adequately controlled with corticosteroids.

引用

页数：7

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