Study objectives: Cocaine abuse is a serious social problem that precipitates a significant number of emergency hospital encounters. To determine the nature of cocaine-related symptoms, we studied patients with cocaine use presenting to all adult services of an urban emergency department. Design: Review of consecutive cases, with analysis of clinical features. Setting: All adult EDs of an urban teaching hospital. Type of participants: Patients acknowledging recent use of cocaine (within 72 hours) and/or with cocaine detected on a toxicologic screen. Measurements and main results: Psychiatric complaints accounted for 44 (30.6%) presentations, followed by neurologic (17.4%), cardiopulmonary (16%), trauma (11.8%), and addiction-related (11.1%) symptoms. Cardiopulmonary symptoms were more frequently associated with intranasal than with IV or smoked cocaine (P = .003). Suicidal intent was the most common psychiatric reason for presentation, occurring in 24 patients (16.6%). Seventeen presented with trauma, including three involved in motor vehicle accidents. Conclusion: Cardiopulmonary symptoms such as chest pain and palpitations may be significantly more frequent in patients who use intranasal cocaine; suicidal intent is common among patients presenting with psychiatric symptoms related to cocaine; and the range of cocaine-related symptoms is varied, including not only psychiatric and cardiopulmonary symptoms but also trauma.
机构:
Univ Penn, Dept Pharmacol, Philadelphia, PA 19104 USAUniv Penn, Dept Pharmacol, Philadelphia, PA 19104 USA
Turner, Jill R.
Ecke, Laurel E.
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Univ Penn, Dept Pharmacol, Philadelphia, PA 19104 USA
Univ Penn, Neurosci Grad Grp, Philadelphia, PA 19104 USAUniv Penn, Dept Pharmacol, Philadelphia, PA 19104 USA
Ecke, Laurel E.
Briand, Lisa A.
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Univ Penn, Dept Pharmacol, Philadelphia, PA 19104 USAUniv Penn, Dept Pharmacol, Philadelphia, PA 19104 USA
Briand, Lisa A.
Haydon, Philip G.
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Tufts Univ, Sch Med, Dept Neurosci, Boston, MA 02111 USAUniv Penn, Dept Pharmacol, Philadelphia, PA 19104 USA
Haydon, Philip G.
Blendy, Julie A.
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Univ Penn, Dept Pharmacol, Philadelphia, PA 19104 USAUniv Penn, Dept Pharmacol, Philadelphia, PA 19104 USA
机构:
St Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, New York, NY USASt Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Marshall, Brandon D. L.
Milloy, M. -J.
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St Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, CanadaSt Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Milloy, M. -J.
Wood, Evan
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St Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Univ British Columbia, Dept Med, Vancouver, BC, CanadaSt Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Wood, Evan
Galea, Sandro
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Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, New York, NY USASt Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Galea, Sandro
Kerr, Thomas
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St Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada
Univ British Columbia, Dept Med, Vancouver, BC, CanadaSt Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z 1Y6, Canada