THE EFFECT OF OLIGODEOXYRIBONUCLEOTIDE TERMINAL PHOSPHATE AND RIBOSE MODIFICATION ON THE INTERACTIONS OF OLIGONUCLEOTIDES WITH CELLS AND INTRACELLULAR STABILITY

被引：11

作者：

ABRAMOVA, TV ^{[1
]}

VLASSOV, VV ^{[1
]}

ZARYTOVA, VF ^{[1
]}

IVANOVA, EM ^{[1
]}

KULIGINA, EA ^{[1
]}

RYTE, AS ^{[1
]}

机构：

[1] ACAD SCI USSR,INST BIOORGAN CHEM,NOVOSIBIRSK 630090,USSR

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期

关键词：

D O I：

10.1080/07328319108046557

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Coupling of lipophilic groups to the termini of oligonucleotides facilitates their binding to mammalian cells and protects them against nucleases attack.

引用

页码：639 / 640

页数：2