SPECIFIC ARRANGEMENTS OF HUMAN SATELLITE-III DNA SEQUENCES IN HUMAN-CHROMOSOMES

被引：85

作者：

BEAUCHAMP, RS ^{[1
]}

MITCHELL, AR ^{[1
]}

BUCKLAND, RA ^{[1
]}

BOSTOCK, CJ ^{[1
]}

机构：

[1] WESTERN GEN HOSP,MRC,CLIN & POPULAT CYTOGENET UNIT,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND

来源：

CHROMOSOMA | 1979年 / 71卷 / 02期

关键词：

D O I：

10.1007/BF00292820

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA was extracted from various rodent-human somatic cell hybrids that contained single or a few human chromosomes. These DNAs were examined by a combination of restriction endonuclease digestion, gel electrophoresis, and filter hybridisation to radioactive satellite DNA probes following transfer of the denatured restriction fragments from a gel to a nitrocellulose filter. In this way the arrangement of sequences homologous to human satellite III were examined on human chromosomes 1, 7, 11, 15, 22 and X. It was found that the distribution of restriction endonuclease sites within satellite III DNA is different on different chromosomes. © 1979 Springer-Verlag.

引用

页码：153 / 166

页数：14

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