STUDIES ON LABELLING PATTERNS OF RNA FROM CEREBRAL CORTEX NUCLEI

被引：16

作者：

DUTTON, GR

CAMPAGNO.AT

MAHLER, HR

MOORE, WJ

机构：

[1] Chemical Laboratories, Indiana University, Bloomington, Indiana

来源：

JOURNAL OF NEUROCHEMISTRY | 1969年 / 16卷 / 06期

关键词：

D O I：

10.1111/j.1471-4159.1969.tb08989.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA labelling patterns in nuclei from rat cerebral cortex were investigated subsequent to intracerebral injection of [3H]uridine. Although there was a rapid uptake of label into the ‘heavy’ regions when nuclear RNA was analysed in density gradients, it was not possible to show conclusive evidence for 455 ribosomal precursor RNA. Methyl‐ation of 18S and 28S nuclear RNA became evident only after 2 hr and did not appear to involve the intermediacy of RNA species of higher molecular weight. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：989 / &

共 42 条

[1] SOME OBSERVATIONS ON INCORPORATION OF PRECURSORS INTO RIBONUCLEIC ACID OF RAT BRAIN [J].