INTERCONVERSION IN-VITRO OF 2 FORMS OF LIVER PHOSPHORYLASE PHOSPHATASE

被引：45

作者：

MERLEVEDE, W

GORIS, J

DEBRANDT, C

机构：

[1] Departement voor Biochemie, Fakulteit voor Geneeskunde, Universiteit te Leuven, Leuven, B-3000

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1969年 / 11卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1969.tb00801.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

When a partially purified dog liver phosphorylase phosphatase preparation was incubated with ATP and Mg ions, its activity increased several fold. A slower activation was observed in the presence of Mg ions only. When the same preparation was preincubated with ATP alone, complete inactivation was obtained. The ATP pretreated enzyme could then be reactivated by Mg++, as well as by ATP and Mg++. The activation and the inactivation of the phosphorylase phosphatase, were shown to be dependent on time, temperature and the concentration of ATP and Mg ions. Neither on the activation nor on the inactivation of the phosphorylase phosphatase could and effect of cyclic 3′ :5′ ‐AMP be observed. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：499 / +

页数：1