ANAPLASTIC LARGE-CELL LYMPHOMA OF TRUE HISTIOCYTIC ORIGIN IN AN INFANT - UNUSUAL CLINICAL, HEMATOLOGICAL, AND CYTOGENETIC FEATURES

被引：3
作者：
FERSTER, A
CORAZZA, F
HEIMANN, P
DEHOU, MF
DEBUSSCHER, C
DEVALCK, C
SARIBAN, E
VAMOS, E
机构：
[1] HOP UNIV BRUGMANN,HAEMATOL LAB,B-1020 BRUSSELS,BELGIUM
[2] HOP UNIV BRUGMANN,PATHOL LAB,B-1020 BRUSSELS,BELGIUM
[3] HOP UNIV BRUGMANN,CYTOGENET LAB,B-1020 BRUSSELS,BELGIUM
来源：
MEDICAL AND PEDIATRIC ONCOLOGY | 1994年 / 22卷 / 02期
关键词：
MALIGNANT HISTOCYTOSIS; ANAPLASTIC LARGE CELL LYMPHOMA; CHROMOSOME-6; CHROMOSOME-8; CHROMOSOME-11; CHROMOSOME-22;
D O I：
10.1002/mpo.2950220218
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We report here the case of a 7-month-old boy who developed anaplastic large cell lymphoma of true histiocytic origin or malignant histiocytosis, with fever, bone and bone marrow infiltration. Usual clinical features were absent. The neoplastic nature of the disease was supported by the presence of clonal chromosomal abnormalities [t(6;8)(p23;p21),der(8)del(8)(q11aq13), der(22) t(11;22) (q13;13)]. Neither B nor T lineage could be demonstrated here. Morphology, ultrastructural analysis, surface antigens expression, and cytogenetics were more specific for the monocyte-macrophage lineage. (C) 1994 Wiley-Liss, Inc.
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页码：147 / 152
页数：6
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