EFFECTS OF NEUROTROPIN ON CONDITIONED AVOIDANCE IN RATS

被引:0
作者
KALYUZHNY, LV [1 ]
LITVINOVA, SV [1 ]
INOZEMTSEV, AN [1 ]
KALYUZHNY, AL [1 ]
ARISTOVA, VV [1 ]
机构
[1] MOSCOW MV LOMONOSOV STATE UNIV,DEPT HIGHER NERVOUS ACT,MOSCOW,RUSSIA
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D O I
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中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Preliminary neurotropin administration improved subsequent conditioned avoidance learning of rats in a shuttle-box: increased the number of conditioned avoidance reactions and decreased their latency in comparison with the control but did not change the number of intertrial responses. <<The demolition>> (5 series of negative reinforcements applied despite of avoidance occurence) caused behavioural stress reactions and inhibited the conditioned and unconditioned avoidance learned reactions. Neurotropin injection before the demolition abolished such disturbances, that having been done after the demolition restored conditioned avoidance. The positive effects of neurotropin were suggested to be due to its antistress property and ability to improve the formation of a result of an acceptor of action.
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页码:371 / 376
页数:6
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