DEVELOPMENTAL-CHANGES OF NERVE GROWTH-FACTOR LEVELS IN THE GRACILE AXONAL DYSTROPHY MOUSE

被引：2
作者：
MATSUI, K [1 ]
FURUKAWA, S [1 ]
SUH, JG [1 ]
WADA, K [1 ]
机构：
[1] GIFU PHARMACEUT UNIV, DEPT MOLEC BIOL, GIFU 502, JAPAN
来源：
NEUROSCIENCE LETTERS | 1994年 / 177卷 / 1-2期
关键词：
NERVE GROWTH FACTOR; MUTANT MOUSE; AXONAL DEGENERATION;
D O I：
10.1016/0304-3940(94)90058-2
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Nerve growth factor (NGF) levels were measured in various tissues of the gracile axonal dystrophy (GAD) mouse. When the disease had fully progressed, the NGF levels in the skeletal muscle, dorsal root ganglion and the spinal cord were decreased. These findings suggest that a reduction of the NGF level is involved in the pathophysiological processes in the GAD mouse.
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收藏
页码：116 / 118
页数：3
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