4TH-DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF SOME PHARMACEUTICAL SUBSTANCES

被引:6
|
作者
IVANOVIC, D
MEDENICA, M
NIVAUDGUERNET, E
GUERNET, M
机构
[1] FAC PHARM BELGRADE, DEPT PHYS CHEM & INSTRUMENTAL METHODS, BELGRADE, YUGOSLAVIA
[2] FAC PHARM CHATENAY MALABRY, CHIM ANALYT & ELECTOCHIM ORGAN LAB, F-92296 CHATENAY MALABRY, FRANCE
关键词
4TH-DERIVATIVE SPECTROPHOTOMETRY; ZERO-CROSSING TECHNIQUE; ACETYLSALICYLIC ACID; ASCORBIC ACID; BUTYLATED HYDROXYANISOLE; CAFFEINE; PARACETAMOL; PHENOBARBITAL; PROMETHAZINE; SALICYLAMIDE; SECOBARBITAL;
D O I
10.1080/00387019508009900
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
In this paper the fourth-derivative spectrophotometric method for the assaying of some pharmaceutical combinations was described. It was analysed the conditions for the determination of certain nan-narcotic analgoantipiretics(acetylsalicylic acid, paracetamol and salicylamide), analeptics (caffeine), vitamins (L-ascorbic acid), antioxidants (butylated hydroxyanisole), sedatives and hypnotics (phenobarbital and secobarbital) and antihistaminics (promethazine). For the determination of numbers of mentioned substances ''zero-crossing'' technique was applied, but for some of them the caracteristic peak amplitude had to be corrected. The investigated criterias were applied for the assaying of these substances in different pharmaceutical combinations. This method is simple, rapid, precize and accurate and could be applied for the quantitative analysis of pharmaceutical preparations.
引用
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页码:557 / 571
页数:15
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