BIOMAGNIFICATION OF BIOASSAY DERIVED 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN EQUIVALENTS

被引：27

作者：

JONES, PD

ANKLEY, GT

BEST, DA

CRAWFORD, R

DEGALAN, N

GIESY, JP

KUBIAK, TJ

LUDWIG, JP

NEWSTED, JL

TILLITT, DE

VERBRUGGE, DA

机构：

[1] MICHIGAN STATE UNIV,INST ENVIRONM TOXICOL,E LANSING,MI 48824

[2] US EPA,ENVIRONM RES LAB,DULUTH,MN 55804

[3] US FISH & WILDLIFE SERV,E LANSING,MI 48823

[4] ECOL RES SERV,ANN ARBOR,MI 48104

[5] US FISH & WILDLIFE SERV,NATL FISHERIES CONTAMINANT RES LAB,COLUMBIA,MO 65201

来源：

CHEMOSPHERE | 1993年 / 26卷 / 06期

关键词：

D O I：

10.1016/0045-6535(93)90206-K

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

In recent years contamination of the Great Lakes ecosystem with planar chlorinated hydrocarbons (PCHs) has attracted considerable concern due to their known reproductive and teratogenic effects. The H4IIE bioassay has been standardized as a means of measuring the biological potency of a PCH mixture as 2,3,7,8-tetrachloro-p-dibenzodioxin equivalents (TCDD-EQ). Using this bioassay we have investigated the biomagnification of TCDD-EQ in a semi-closed ecosystem. The biomagnification of TCDD-EQ is demonstrated and results indicate that the food chain is the major pathway for TCDD-EQ through this ecosystem. The H4IIE assay system is demonstrated to be a viable integrative measure of the total concentration of TCDD-EQ in different trophic levels.

引用

页码：1203 / 1212

页数：10

共 25 条

[1] BIOASSAY-DERIVED 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN EQUIVALENTS IN PCB-CONTAINING EXTRACTS FROM THE FLESH AND EGGS OF LAKE-MICHIGAN CHINOOK SALMON (ONCORHYNCHUS-TSHAWYTSCHA) AND POSSIBLE IMPLICATIONS FOR REPRODUCTION [J].