EFFECT OF PROPYL GALLATE FEEDING ON GLUTATHIONE CONTENT IN AGING ZAPRIONUS-PARAVITTIGER (DIPTERA)

被引：0
作者：
BAINS, JS [1 ]
SHARMA, SP [1 ]
GARG, SK [1 ]
机构：
[1] Guru Nanak Dev Univ, Dept Mol Biol & Biochem, Amritsar 143005, Punjab, INDIA
来源：
GERONTOLOGY | 1992年 / 38卷 / 04期
关键词：
ANTIOXIDANT; PROPYL GALLATE; MITOCHONDRIA; GLUTATHIONE;
D O I：
暂无
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Glutathione content increased during the reproductive period and decreased thereafter up to the 43rd day of age in whole body as well as mitochondrial homogenates of ageing Zaprionus paravittiger. However, females exhibited higher levels of glutathione as compared to males. In whole body homogenates. propyl gallate (PG: 25 mug/ml) increased the glutathione content significantly up to the 22nd day of life whereas in mitochondria it increased during all age intervals in the two sexes with the exception of the 36th and 43rd day of survival in males. In conclusion, the higher level of glutathione on PG feeding might be one of the factors leading to the prolonged life span of flies.
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页码：192 / 195
页数：4
相关论文
共 12 条
[1]   EFFECT OF CATALASE INACTIVATION ON LEVELS OF INORGANIC PEROXIDES, SUPEROXIDE-DISMUTASE, GLUTATHIONE, OXYGEN-CONSUMPTION AND LIFE-SPAN IN ADULT HOUSEFLIES (MUSCA-DOMESTICA) [J].
ALLEN, RG ;
FARMER, KJ ;
SOHAL, RS .
BIOCHEMICAL JOURNAL, 1983, 216 (02) :503-506
[2]   EFFECTS OF PARAQUAT ADMINISTRATION ON LONGEVITY, OXYGEN-CONSUMPTION, LIPID-PEROXIDATION, SUPEROXIDE-DISMUTASE, CATALASE, GLUTATHIONE-REDUCTASE, INORGANIC PEROXIDES AND GLUTATHIONE IN THE ADULT HOUSEFLY [J].
ALLEN, RG ;
FARMER, KJ ;
NEWTON, RK ;
SOHAL, RS .
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1984, 78 (02) :283-288
[3]  
BAINS JS, 1990, THESIS DEV U AMRITSA, P1
[4]   HYDROPEROXIDE METABOLISM IN MAMMALIAN ORGANS [J].
CHANCE, B ;
SIES, H ;
BOVERIS, A .
PHYSIOLOGICAL REVIEWS, 1979, 59 (03) :527-605
[5]   GLUTATHIONE CONTENTS OF TISSUES IN THE AGING MOUSE [J].
HAZELTON, GA ;
LANG, CA .
BIOCHEMICAL JOURNAL, 1980, 188 (01) :25-30
[6]   CHEMI-LUMINESCENT MEASUREMENT OF FREE-RADICALS AND ANTIOXIDANT MOLECULAR-PROTECTION INSIDE LIVING RAT-MITOCHONDRIA [J].
LIPPMAN, RD .
EXPERIMENTAL GERONTOLOGY, 1980, 15 (05) :339-&
[7]   GLUTATHIONE [J].
MEISTER, A ;
ANDERSON, ME .
ANNUAL REVIEW OF BIOCHEMISTRY, 1983, 52 :711-760
[8]  
PACIFICI RE, 1991, GERONTOLOGY, V37, P166
[9]   PROPYL GALLATE DELAYS SENESCENCE IN DROSOPHILA-MELANOGASTER [J].
RUDDLE, DL ;
YENGOYAN, LS ;
MIQUEL, J ;
MARCUSON, R ;
FLEMING, JE .
AGE, 1988, 11 (02) :54-58
[10]  
SHARMA SP, IN PRESS AGE
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