EFFECTS OF REPEATED ADMINISTRATION OF CHLORDIAZEPOXIDE ON SPONTANEOUS LOCOMOTOR-ACTIVITY IN MICE

被引：56

作者：

SANSONE, M

机构：

[1] Laboratorio di Psicobiologia e Psicofarmacologia, C.N.R., Roma, I-00198

来源：

PSYCHOPHARMACOLOGY | 1979年 / 66卷 / 01期

关键词：

Activity; Chlordiazepoxide; Repeated administration;

D O I：

10.1007/BF00431999

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Spontaneous locomotor activity has been studied in mice treated with single or repeated doses (five daily injections) of chlordiazepoxide. The repeated administration enhanced the stimulatory action of the lower doses of the drug, while the depressant effect of the higher doses was reduced. © 1979 Springer-Verlag.

引用

收藏

页码：109 / 110

页数：2

相关论文

共 14 条

[1] MODIFICATION OF DEPRESSANT AND DISINHIBITORY ACTION OF FLURAZEPAM DURING SHORT-TERM TREATMENT IN RAT [J].

CANNIZZARO, G ;

VITIKOVA, T ;

NIGITO, S ;

PROVENZANO, PM .

PSYCHOPHARMACOLOGIA, 1972, 26 (02) :173-+

[2]

COOK L, 1975, BEHAVIORAL PHARM CUR, P265

[3] BEHAVIORAL EFFECTS OF BENZODIAZEPINES [J].

DANTZER, R .

BIOBEHAVIORAL REVIEWS, 1977, 1 (02) :71-86

[4]

GOLDBERG MORTON E., 1967, LIFE SCI, V6, P481, DOI 10.1016/0024-3205(67)90051-3

[5] CHLORDIAZEPOXIDE EFFECTS ON REACTIONS TO NOVELTY AND ACTIVITY WITH AND WITHOUT PRIOR DRUG EXPERIENCE [J].

HUGHES, RN ;

GREIG, AM .

PSYCHOPHARMACOLOGIA, 1975, 42 (03) :289-292

[6] EFFECTS OF CHLORDIAZEPOXIDE UPON HABITUATION OF OPEN-FIELD BEHAVIOR IN WHITE RATS [J].

IWAHARA, S ;

SAKAMA, E .

PSYCHOPHARMACOLOGIA, 1972, 27 (03) :285-&

[7] EXTINCTION OF FEAR .2. EFFECTS OF CHLORDIAZEPOXIDE AND CHLORPROMAZINE ON FEAR AND EXPLORATORY BEHAVIOUR IN RATS [J].

KUMAR, R .

PSYCHOPHARMACOLOGIA, 1971, 19 (03) :297-&

[8]

MARGULES D L, 1968, Psychopharmacologia, V13, P74, DOI 10.1007/BF00401620

[9] EFFECTS OF CENTRALLY ACTING DRUGS ON EXPLORATORY BEHAVIOUR IN RATS [J].

MARRIOTT, AS ;

SPENCER, PSJ .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1965, 25 (02) :432-&

[10]

RANDALL LO, 1968, PSYCHOPHARMACOLOGY R, P153