FULMINANT METOCLOPRAMIDE INDUCED NEUROLEPTIC MALIGNANT SYNDROME RAPIDLY RESPONSIVE TO INTRAVENOUS DANTROLENE

被引：14

作者：

HENDERSON, A

LONGDON, P

机构：

[1] Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland

[2] Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland

来源：

AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE | 1991年 / 21卷 / 05期

关键词：

METOCLOPRAMIDE; NEUROLEPTIC MALIGNANT SYNDROME; DANTROLENE;

D O I：

10.1111/j.1445-5994.1991.tb01381.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of fulminant neuroleptic malignant syndrome in a man aged 70 developing within 12 hours of starting six-hourly intravenous metoclopramide. The muscle rigidity and hyperpyrexia were unresponsive to intravenous benztropine but resolved within one hour of intravenous dantrolene 2 mg/kg. Within six hours the patient had a partial relapse which resolved completely following further intravenous dantrolene 2 mg/kg. This case demonstrates that the rapid effect of intravenous dantrolene can be life saving in fulminant neuroleptic malignant syndrome.

引用

页码：742 / 743

页数：2

共 11 条

[1] THE NEUROLEPTIC MALIGNANT SYNDROME - PRESENTATION AND TREATMENT [J].