STEREOSELECTIVE SYNTHESIS OF INOSITOL PHOSPHATES

被引：38

作者：

LEY, SV

机构：

[1] Department of Chemistry, Imperial College of Science, Technology and Medicine, London

来源：

PURE AND APPLIED CHEMISTRY | 1990年 / 62卷 / 10期

关键词：

D O I：

10.1351/pac199062102031

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pseudomonas putida oxidation of benzene affords cis-3,5-cyclohexadiene-l,2-diol (1) which serves as a novel precursor for the syntheses of several natural products including (+)-pinitol, (+)-conduritol F, D-(-)-myo-inositol 1,4,5-trisphosphate and D-mya-inositol 1-phosphate. The versatility of this approach is further demonstrated by the preparation of other functionalised cyclitol derivatives, in particular 6-deoxy, 6-deoxy-6-fluoro, 6-deoxy-6-methyl and 6-methyl inositol 1,4,5-trisphosphates. © 1990, IUPAC.

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页码：2031 / 2034

页数：4

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